| | Day | Time | | Opponent | Score | | Record |
| February |
| | 5 | 4:00 PM | vs. | Temple | L-0-8 | | 0-1 |
| | UTPB Complex |
| | | 6:00 PM | vs. | Vernon | W-2-0 | | 1-1 |
| | MC: Meghan Penneau throws no-hitter |
| | 6 | | vs. | Temple | L-5-11 | | 1-2 |
| | | | vs. | Ranger | W-2-0 | | 2-2 |
| | 8 | 1:00 PM | @ | Lubbock Christian | CNCL | | |
| | | Game 2 | @ | Lubbock Christian | CNCL | | |
| | 13 | 12:00 PM | vs. | NCTC | W-1-0 | | 3-2 |
| | Odessa/Midland Round Robin |
| | | 2:00 PM | vs. | Cisco | W-3-0 | | 4-2 |
| | Field 7 * Claire Molina pitches perfect game |
| | | 4:00 PM | vs. | McLennan | W-5-0 | | 5-2 |
| | Field 7 * AJ Woodward strikes out 15 hitters |
| | 19 | | vs. | Pratt Community College | W-11-0 | | 6-2 |
| | Midland College Classic * Feb. 19-20 |
| | | 1:00 PM | vs. | Seminole State College | L-1-5 | | 6-3 |
| | Midland College Classic |
| | | 8:30 PM | vs. | Trinidad State Junior College | W-7-1 | | 7-3 |
| | Midland College Classic * Feb. 19-20 |
| | 20 | 2:00 PM | vs. | Blinn College | W-4-1 | | 8-3 |
| | Midland College Classic * Feb. 19-20 |
| | | 4:30 PM | vs. | Lubbock Christian Univ. JV | W-10-0 (5) | | 9-3 |
| | Midland College Classic * Feb. 19-20 |
| | 26 | | vs. | Paris Junior College | W-4-1 | | 10-3 |
| | San Jacinto Tourney * Feb. 26-27 |
| | | | vs. | Paris Junior College | W-9-1 | | 11-3 |
| | San Jacinto tourney * Feb. 26-27 |
| | 27 | 8:00 AM | @ | San Jacinto College | W-4-3 | | 12-3 |
| | | 4:00 PM | vs. | Galveston College | L-3-4 (9) | | 12-4 |
| | 28 | | vs. | Angelina College | L-2-3 | | 12-5 |
| | | Game 2 | vs. | Angelina College | L-3-4 | | 12-6 |
| March |
| | 8 | 2:00 PM | vs. | Temple | W-2-1 (9) | | 13-6 |
| | MC: Kamaka walk-off homerun in bottom of 9th |
| | | Game 2 | vs. | Temple | W-12-4 (6) | | 14-6 |
| | 13 | | vs. | Barton County Community College | W-12-1 | | 15-6 |
| | Midwest JUCO Classic * March 12-13 |
| | | | vs. | Northern Oklahoma College - Enid | W-7-5 | | 16-6 |
| | Midwest JUCO Classic * March 12-13 |
| | | | vs. | Coffeyville Community College | W-8-0 (5) | | 17-6 |
| | 15 | | vs. | Connors State | W-4-1 | | 18-6 |
| | | | vs. | Maple Woods | W-5-0 | | 19-6 |
| | | | vs. | Northeastern State | W-6-1 | | 20-6 |
| | | 1:00 PM | vs. | Rose State College | W-8-4 | | 21-6 |
| | | Game 2 | vs. | Rose State College | W-10-0 (6) | | 22-6 |
| * | 20 | 1:00 PM | vs. | Western Texas | W-20-0 (5) | | 23-6 1-0 |
| * | | Game 2 | vs. | Western Texas | W-9-5 | | 24-6 2-0 |
| * | 21 | 1:00 PM | vs. | Western Texas | W-11-5 | | 25-6 3-0 |
| * | | Game 2 | vs. | Western Texas | W-6-3 | | 26-6 4-0 |
| * | 26 | 4:00 PM | vs. | Howard | W-9-3 | | 27-6 5-0 |
| * | | Game 2 | vs. | Howard | W-8-3 | | 28-6 6-0 |
| * | 27 | 1:00 PM | @ | Howard | W-9-1 (5) | | 29-6 7-0 |
| * | | Game 2 | @ | Howard | W-5-1 | | 30-6 8-0 |
| April |
| * | 1 | 2:00 PM | vs. | Frank Phillips | W-8-0 (5) | | 31-6 9-0 |
| * | | Game 2 | vs. | Frank Phillips | W-9-1 (6) | | 32-6 10-0 |
| * | 2 | 11:00 AM | vs. | Clarendon | W-3-2 | | 33-6 11-0 |
| * | | Game 2 | vs. | Clarendon | W-12-1 (5) | | 34-6 12-0 |
| * | 9 | 4:00 PM | vs. | Odessa | W-10-5 | | 35-6 13-0 |
| * | | Game 2 | vs. | Odessa | W-3-2 | | 36-6 14-0 |
| * | 10 | 1:00 PM | @ | Odessa | W-2-1 | | 37-6 15-0 |
| * | | Game 2 | @ | Odessa | L-3-4 | | 37-7 15-1 |
| * | 23 | 1:00 PM | @ | Clarendon | L-0-2 | | 37-8 15-2 |
| * | | Game 2 | @ | Clarendon | W-9-4 | | 38-8 16-2 |
| * | 24 | 12:00 PM | @ | Frank Phillips | W-4-1 | | 39-8 17-2 |
| * | | Game 2 | @ | Frank Phillips | W-6-3 | | 40-8 18-2 |
| * | 30 | 4:00 PM | vs. | El Paso | W-16-0 | | 41-8 19-2 |
| * | | Game 2 | vs. | El Paso | W-9-1 | | 42-8 20-2 |
| May |
| * | 1 | 1:00 PM | vs. | El Paso | W-10-1 | | 43-8 21-2 |
| * | | Game 2 | vs. | El Paso | W-14-1 | | 44-8 22-2 |
| | 8 | 11:30 AM | vs. | Howard | W-12-4 | | 45-8 |
| | R5 West Tournament * #1 Midland vs #4 Howard |
| | | 3:00 PM | vs. | Odessa | L-0-4 | | 45-9 |
| | Region 5 West Tournament |
| | 9 | 11:00 AM | vs. | Clarendon | W-7-2 | | 46-9 |
| | Region 5 West Tournament * Loser is eliminated |
| | | 1:00 PM | vs. | Odessa | L-3-5 | | 46-10 |
| | R5 West Tournament * OC vs MC/CC winner in double elimination format |
