| | Day | Time | | Opponent | Score | | Record |
| August |
| | 27 | 11:00AM | vs. | Paris Junior College | L-25-18,25-22,24-26,25-18 | | 0-1 |
| | Brookhaven Tournament * Aug. 27-28 |
| | | 5:00PM | vs. | Hill | L-20-25,26-24,13-25,21-25 | | 0-2 |
| | Brookhaven Tournament * Aug. 27-28 |
| | 28 | 9:00AM | @ | Brookhaven | L-26-24,25-12,25-20 | | 0-3 |
| | Brookhaven Tournament * Aug. 27-28 |
| | | 1:00PM | vs. | Trinity Valley CC | L-20-25,25-21,25-15,25-23 | | 0-4 |
| | Brookhaven Tournament * Aug. 27-28 |
| | 31 | 6:15PM | @ | Lubbock Christian Univ. JV | W-13-25,15-25,11-25 | | 1-4 |
| September |
| | 3 | 10:15AM | vs. | Ranger | W-20-25,24-26 | | 2-4 |
| | Vernon Tourney * Sept 3-4 |
| | | 11:30AM | vs. | Fort Scott CC | W-25-21,23-25,12-15 | | 3-4 |
| | Vernon Tourney * Sept. 3-4 |
| | | 2:00PM | vs. | Eastfield | L-25-13,25-22 | | 3-5 |
| | Vernon Tourney * Sept 3-4 |
| | 4 | 12:45PM | vs. | Richland | W-11-25,12-25 | | 4-5 |
| | Vernon Tourney * Sept 3-4 |
| | | 3:15PM | @ | Vernon | W-11-25,25-19,10-15 | | 5-5 |
| | Vernon Tourney * Sept 3-4 |
| | 8 | 6:00PM | @ | Ranger | W-18-25,25-23,17-25,25-17,10-15 | | 6-5 |
| | 10 | 4:00PM | vs. | Trinidad State Junior College | W-15-25,22-25,15-25 | | 7-5 |
| | Otero Tournament * Sept. 10-11 |
| | | 6:00PM | @ | Otero Junior College | W-23-25,24-26,20-25 | | 8-5 |
| | Otero Tournament * Sept. 10-11 |
| | 11 | 9:00AM | vs. | Colorado Northwestern CC | W-10-25,12-25,12-25 | | 9-5 |
| | Otero Tournament * Sept. 10-11 |
| | | 11:00AM | vs. | Air Force Prep | W-15-25,24-26,21-25 | | 10-5 |
| | Otero Tournament * Sept. 10-11 |
| | 17 | 11:45AM | vs. | Tyler College | W-21-25,15-25,14-25 | | 11-5 |
| | NCTC Tourney * Sept. 17-18 |
| | | 4:45PM | @ | NCTC | W-27-29,20-25,22-25 | | 12-5 |
| | NCTC Tourney * Sept. 17-18 |
| | 18 | 1:30PM | vs. | Pratt Community College | L-25-20,25-21,25-19 | | 12-6 |
| | NCTC Tourney * Sept. 17-18 |
| | | 4:45PM | vs. | Midland | L-25-17,25-21,25-23 | | 12-7 |
| | NCTC Tourney * Sept. 17-18 |
| | 20 | 6:00PM | vs. | Ranger | W-25-15,25-22,25-17 | | 13-7 |
| * | 22 | | @ | Frank Phillips | L-25-15,25-9,25-14 | | 13-8 0-1 |
| * | 29 | | @ | NMMI | L-25-19,25-11,25-23 | | 13-9 0-2 |
| October |
| | 4 | 6:00PM | vs. | Lubbock Christian Univ. JV | W-25-11,25-7,25-10 | | 14-9 |
| * | 6 | | vs. | Clarendon | W-25-20,25-23,25-20 | | 15-9 1-2 |
| | 8 | | vs. | Cedar Valley | W-25-12,25-17,25-12 | | 16-9 |
| | 9 | | vs. | Cedar Valley | W-25-18,25-13,25-9 | | 17-9 |
| * | 13 | 7:00PM | vs. | Midland | L-25-18,22-25,14-25,14-25 | | 17-10 1-3 |
| | Midland Coach Kimberly Boone earns 100th career victory (100-47) |
| | 15 | 11:00AM | vs. | Dodge City Community College | L-23-25,25-17,24-26,25-18,15-9 | | 17-11 |
| | Midland Tournament * Oct. 15-16 |
| | | 6:00PM | @ | Midland | L-25-16,25-15,25-19 | | 17-12 |
| | Midland Tournament * Oct. 15-16 |
| | 16 | 8:00AM | vs. | Coastal Bend | W-23-25,25-16,20-25,19-25 | | 18-12 |
| | Midland Tournament * Oct. 15-16 |
| | | 10:00AM | vs. | Cisco | W-25-22,15-25,25-19,21-25,15-10 | | 19-12 |
| | Midland Tournament * Oct. 15-16 |
| * | 23 | | vs. | Frank Phillips | L-25-23,15-25,18-25,24-26 | | 19-13 1-4 |
| * | 27 | | vs. | NMMI | L-26-28,11-25,23-25 | | 19-14 1-5 |
| * | 30 | | @ | Clarendon | W-11-25,17-25,21-25 | | 20-14 2-5 |
| November |
| * | 1 | | @ | Midland | L-25-13,25-17,25-12 | | 20-15 2-6 |
| | 4 | | vs. | TBA | | | |
| | Region 5 West Tournament * Nov. 4-6, 2010 * Roswell, NM |
| | 6 | 10:00AM | vs. | Midland | L-24-26,14-25,16-25 | | 20-16 |
| | Region 5 West Championship * #1 Midland, #4 WTC |
